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Vaccination: Varicella-Zoster Virus Vaccine
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Total 2073 results found since Jan 2013.
Evaluating public interest in herpes zoster in Germany by leveraging the internet: a retrospective search data analysis
CONCLUSIONS: The study demonstrated that evaluating internet search data is a viable method for assessing public interest in HZ, thereby identifying areas of unmet need to support targeted public health campaigns.PMID:37580664 | DOI:10.1186/s12889-023-16463-4
Source: Herpes - August 14, 2023 Category: Infectious Diseases Authors: Alphina Kain Linda Tizek Hannah Wecker Fabian Walln öfer Tilo Biedermann Alexander Zink Source Type: research
Herpes zoster and long-term vascular risk: a retrospective cohort study
Sci Rep. 2023 Feb 9;13(1):2364. doi: 10.1038/s41598-023-29667-w.ABSTRACTHerpes zoster (HZ) represents a serious health problem in the general population due to its abundance and complications. Stroke and acute myocardial infarction are well-documented short-term complications of HZ, primarily due to vasculopathy in the cerebral and coronary arteries. However, no major study to date has specifically demonstrated that HZ is a long-term risk factor for all Major Adverse Cardiac and Cerebrovascular Events (MACCE). A retrospective cohort study was conducted analyzing the association between HZ and MACCE. We compared HZ patients...
Source: Herpes - February 9, 2023 Category: Infectious Diseases Authors: Amir Horev Anat Horev Adi Gordon-Irshai Michal Gordon Nicolas Andre Gal Ifergane Source Type: research
Exploring the purine core of 3'-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics.
Abstract
A series of new nucleoside analogues based on a C-3 branched ethynyl sugar derivative as present in 3'-C-ethynylcytidine (ECyd) and -adenosine (EAdo), combined with modified purine bases was synthetized and evaluated against a broad array of viruses and tumour cell lines. The pronounced cytostatic activity of EAdo was confirmed. EAdo and its 2,6-diaminopurine analogue showed inhibitory activity against vaccinia virus (EC50: 0.31 and 51μM, respectively). Derivative 10 on the other hand was found active against varicella zoster virus (EC50: 4.68μM).
PMID: 26965865 [PubMed - as supplied by publisher]
Source: Bioorganic and Medicinal Chemistry Letters - March 3, 2016 Category: Chemistry Authors: Hulpia F, Balzarini J, Schols D, Andrei G, Snoeck R, Van Calenbergh S Tags: Bioorg Med Chem Lett Source Type: research
Herpes zoster and the search for an effective vaccine.
This article reviews VZV pathogenesis, host responses and current vaccines available to prevent herpes zoster. This article is protected by copyright. All rights reserved.
PMID: 27164323 [PubMed - as supplied by publisher]
Source: Clinical and Developmental Immunology - May 9, 2016 Category: Allergy & Immunology Authors: Arnold N, Messaoudi I Tags: Clin Exp Immunol Source Type: research
Fight Aging! Newsletter, May 25th 2020
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation.
Lin28 as a Target for Nerve Regeneration
https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/
Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitochondri...
Source: Fight Aging! - May 24, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed.
The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Vaccination against the herpes zoster virus
CONCLUSIONS: We have a safe and effective vaccine against the herpes zoster virus that allows us to protect the most vulnerable population groups against this virus.PMID:37573820 | PMC:PMC10428030 | DOI:10.1016/j.aprim.2023.102710
Source: Atencion Primaria - August 13, 2023 Category: Primary Care Authors: Jos é Javier Gómez Marco Susana Mart ín Martín Pablo Aldaz Herce Ana Pilar Javierre Miranda Coro S ánchez Hernández Source Type: research
